Omeprazole + Sodium Bicarbonate is a combination used primarily for the treatment of gastroesophageal reflux disease (GERD), acid reflux, and peptic ulcers, similar to sucralfate, but it works differently.

Applications:

• Treats GERD, heartburn, and acid reflux.
• Helps heal and prevent ulcers by reducing stomach acid production.
• Used to manage Zollinger-Ellison syndrome, where excess acid is produced.

Side Effects:

• Common: headache, nausea, diarrhea, and abdominal pain.
• Rare but serious: severe allergic reactions, kidney problems, and bone fractures with long-term use.
• Prolonged use can lead to vitamin B12 deficiency and low magnesium levels.

Unlike sucralfate, which forms a protective layer over ulcers, omeprazole with sodium bicarbonate works by reducing stomach acid to help heal and prevent damage.