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Palonosetron Hydrochloride
Palonosetron Hydrochloride is a long-acting 5-HT3 receptor antagonist used to prevent nausea and vomiting.
Applications:
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Prevents acute and delayed nausea/vomiting from moderately to highly emetogenic chemotherapy.
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Also used for postoperative nausea and vomiting.
Side Effects:
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Common: headache, constipation, dizziness.
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Serious (rare): QT prolongation, hypersensitivity reactions.
Br120.00Palonosetron Hydrochloride
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00Fosaprepitant
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Chlorpromazine Hydrochloride
Applications:
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Psychosis (schizophrenia, mania)
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Severe nausea/vomiting
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Intractable hiccups
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Acute agitation/sedation
Side Effects:
Common: Drowsiness, dry mouth, constipation, low BP
Serious:-
Muscle spasms (EPS), tardive dyskinesia
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Neuroleptic malignant syndrome (NMS)
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QT prolongation → heart rhythm risk
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Seizures, confusion (elderly)
Avoid in: Glaucoma, Parkinson’s, heart rhythm issues.
Br120.00Chlorpromazine Hydrochloride
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00Aprepitant
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Omeprazole
Applications:
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Treats severe GERD/ulcers (when oral therapy fails)
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Manages Zollinger-Ellison syndrome (acid hypersecretion)
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Prevents acid aspiration during surgery
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Reduces rebleeding risk after endoscopic treatment
Side Effects:
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Common: Headache, nausea, injection-site pain
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Serious (rare): Kidney injury, low magnesium, bone fractures (long-term use)
Note: Requires kidney/magnesium monitoring with prolonged IV use. Administered once daily (40mg). Brands include Losec® IV and generics.
Br120.00Omeprazole
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Famotidine
Applications:
- Used to treat gastroesophageal reflux disease (GERD), ulcers, and conditions caused by excess stomach acid like Zollinger-Ellison syndrome.
- Helps reduce stomach acid production to promote healing and relieve symptoms like heartburn.
Side Effects:
- Headache, dizziness, and constipation.
- In rare cases, can cause confusion, especially in older adults or those with kidney issues.
Famotidine is effective for managing acid-related digestive disorders and is generally well-tolerated. However, like any medication, it can cause side effects, especially in individuals with pre-existing kidney conditions.
Br120.00Famotidine
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