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Lactulose
Lactulose is an osmotic laxative used to treat constipation and manage hepatic encephalopathy.
Applications:
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Relieves chronic constipation by drawing water into the bowel.
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Reduces blood ammonia levels in patients with liver disease (hepatic encephalopathy).
Side Effects:
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Common: bloating, gas, abdominal cramps, diarrhea.
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Serious (rare): electrolyte imbalance with prolonged use or high doses.
Br120.00Lactulose
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Metoclopramide Hydrochloride
Metoclopramide Hydrochloride is a dopamine antagonist used to treat nausea, vomiting, and delayed gastric emptying.
Applications:
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Treats nausea and vomiting from various causes, including chemotherapy and migraines.
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Manages gastroparesis by enhancing stomach motility.
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Used for GERD when other treatments fail.
Side Effects:
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Common: drowsiness, fatigue, restlessness.
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Serious (rare): tardive dyskinesia (involuntary movements), Parkinson-like symptoms, depression.
Br120.00Metoclopramide Hydrochloride
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00Fosaprepitant
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00Aprepitant
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Simethicone + Algerines citrate
Applications:
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Bloating & Gas Relief:
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Simethicone: Breaks down gas bubbles in the gut (anti-foaming agent).
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Alverine Citrate: Relieves intestinal spasms (smooth muscle relaxant).
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Irritable Bowel Syndrome (IBS): Reduces cramping, distension, and discomfort.
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Functional GI Disorders: Eases symptoms of dyspepsia or diverticular disease.
Side Effects:
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Simethicone: Generally side-effect-free (not absorbed systemically).
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Alverine Citrate:
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Mild: Dizziness, nausea, headache.
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Rare: Allergic reactions (rash, itching).
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Br120.00Simethicone + Algerines citrate
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Darifenacin
Applications:
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Overactive Bladder (OAB): Treats frequent urination, urgency, and incontinence.
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Neurogenic Detrusor Overactivity: Manages bladder control issues in neurological conditions (e.g., MS, spinal cord injury).
Side Effects:
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Common: Dry mouth, constipation, blurred vision, dizziness.
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Serious (Rare):
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Severe allergic reactions (rash, swelling).
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Worsening glaucoma (caution in patients with eye conditions).
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Urinary retention (in men with prostate enlargement).
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Br120.00Darifenacin
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