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Promethazine Hydrochloride
Promethazine Hydrochloride is an antihistamine with antiemetic, sedative, and anticholinergic properties.
Applications:
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Treats nausea, vomiting, and motion sickness.
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Used as a sedative or for allergy symptoms.
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Sometimes used pre/post-surgery for nausea control.
Side Effects:
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Common: drowsiness, dry mouth, dizziness.
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Serious (rare): respiratory depression (especially in children), severe tissue damage if injected improperly.
Br120.00
Promethazine Hydrochloride
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Granisetron Hydrochloride
Granisetron Hydrochloride is a 5-HT3 receptor antagonist used to prevent and treat nausea and vomiting.
Applications:
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Prevents nausea and vomiting from chemotherapy and radiation therapy.
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Used postoperatively to manage nausea and vomiting.
Side Effects:
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Common: headache, constipation, dizziness.
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Serious (rare): QT prolongation, allergic reactions.
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Granisetron Hydrochloride
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
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Fosaprepitant
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Chlorpromazine Hydrochloride
Applications:
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Psychosis (schizophrenia, mania)
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Severe nausea/vomiting
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Intractable hiccups
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Acute agitation/sedation
Side Effects:
Common: Drowsiness, dry mouth, constipation, low BP
Serious:-
Muscle spasms (EPS), tardive dyskinesia
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Neuroleptic malignant syndrome (NMS)
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QT prolongation → heart rhythm risk
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Seizures, confusion (elderly)
Avoid in: Glaucoma, Parkinson’s, heart rhythm issues.
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Chlorpromazine Hydrochloride
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
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Aprepitant
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Simethicone + Algerines citrate
Applications:
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Bloating & Gas Relief:
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Simethicone: Breaks down gas bubbles in the gut (anti-foaming agent).
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Alverine Citrate: Relieves intestinal spasms (smooth muscle relaxant).
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Irritable Bowel Syndrome (IBS): Reduces cramping, distension, and discomfort.
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Functional GI Disorders: Eases symptoms of dyspepsia or diverticular disease.
Side Effects:
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Simethicone: Generally side-effect-free (not absorbed systemically).
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Alverine Citrate:
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Mild: Dizziness, nausea, headache.
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Rare: Allergic reactions (rash, itching).
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Br120.00
Simethicone + Algerines citrate
Br120.00 Select options This product has multiple variants. The options may be chosen on the product page -