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Cascara sagrada
Cascara Sagrada is a natural stimulant laxative derived from the bark of the Rhamnus purshiana tree.
Applications:
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Used to relieve occasional constipation.
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Sometimes included in herbal detox or colon cleanse products.
Side Effects:
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Common: abdominal cramps, diarrhea.
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Serious (with long-term use): electrolyte imbalance, dependency, liver damage (rare).
Br120.00
Cascara sagrada
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Promethazine Hydrochloride
Promethazine Hydrochloride is an antihistamine with antiemetic, sedative, and anticholinergic properties.
Applications:
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Treats nausea, vomiting, and motion sickness.
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Used as a sedative or for allergy symptoms.
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Sometimes used pre/post-surgery for nausea control.
Side Effects:
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Common: drowsiness, dry mouth, dizziness.
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Serious (rare): respiratory depression (especially in children), severe tissue damage if injected improperly.
Br120.00
Promethazine Hydrochloride
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Palonosetron Hydrochloride
Palonosetron Hydrochloride is a long-acting 5-HT3 receptor antagonist used to prevent nausea and vomiting.
Applications:
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Prevents acute and delayed nausea/vomiting from moderately to highly emetogenic chemotherapy.
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Also used for postoperative nausea and vomiting.
Side Effects:
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Common: headache, constipation, dizziness.
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Serious (rare): QT prolongation, hypersensitivity reactions.
Br120.00
Palonosetron Hydrochloride
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Meclizine Hydrochloride
Meclizine Hydrochloride is an antihistamine used to treat motion sickness and vertigo.
Applications:
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Prevents and treats nausea, vomiting, and dizziness from motion sickness.
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Manages vertigo from inner ear disorders like Ménière’s disease.
Side Effects:
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Common: drowsiness, dry mouth, and blurred vision.
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Serious (rare): confusion, especially in older adults.
Br120.00
Meclizine Hydrochloride
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00
Fosaprepitant
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00
Aprepitant
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