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Promethazine Hydrochloride
Promethazine Hydrochloride is an antihistamine with antiemetic, sedative, and anticholinergic properties.
Applications:
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Treats nausea, vomiting, and motion sickness.
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Used as a sedative or for allergy symptoms.
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Sometimes used pre/post-surgery for nausea control.
Side Effects:
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Common: drowsiness, dry mouth, dizziness.
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Serious (rare): respiratory depression (especially in children), severe tissue damage if injected improperly.
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Promethazine Hydrochloride
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Meclizine Hydrochloride
Meclizine Hydrochloride is an antihistamine used to treat motion sickness and vertigo.
Applications:
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Prevents and treats nausea, vomiting, and dizziness from motion sickness.
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Manages vertigo from inner ear disorders like Ménière’s disease.
Side Effects:
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Common: drowsiness, dry mouth, and blurred vision.
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Serious (rare): confusion, especially in older adults.
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Meclizine Hydrochloride
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
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Fosaprepitant
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
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Aprepitant
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Simethicone + Algerines citrate
Applications:
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Bloating & Gas Relief:
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Simethicone: Breaks down gas bubbles in the gut (anti-foaming agent).
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Alverine Citrate: Relieves intestinal spasms (smooth muscle relaxant).
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Irritable Bowel Syndrome (IBS): Reduces cramping, distension, and discomfort.
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Functional GI Disorders: Eases symptoms of dyspepsia or diverticular disease.
Side Effects:
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Simethicone: Generally side-effect-free (not absorbed systemically).
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Alverine Citrate:
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Mild: Dizziness, nausea, headache.
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Rare: Allergic reactions (rash, itching).
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Br120.00
Simethicone + Algerines citrate
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Propantheline Bromide
Applications:
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Peptic Ulcers: Reduces gastric acid secretion (adjunct therapy).
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Hyperhidrosis: Controls excessive sweating (off-label).
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GI Spasms: Manages irritable bowel syndrome (IBS) and diverticulitis.
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Urinary Incontinence: Treats overactive bladder (less common now).
Side Effects:
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Common: Dry mouth, blurred vision, constipation, drowsiness.
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Serious (Rare):
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Urinary retention (risk in prostate enlargement).
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Tachycardia (fast heart rate).
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Glaucoma exacerbation (avoid in narrow-angle glaucoma).
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Br120.00
Propantheline Bromide
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Omeprazole
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and conditions related to excess stomach acid.
- Helps reduce acid production in the stomach, promoting healing and alleviating symptoms like heartburn.
Side Effects:
- Headache, diarrhea, nausea, and abdominal pain.
- In rare cases, it can cause kidney issues, low magnesium levels, or vitamin B12 deficiency with long-term use.
Omeprazole is effective in managing acid-related gastrointestinal conditions but may cause mild side effects like headache and stomach discomfort. Serious side effects are rare but should be monitored, particularly in individuals with kidney problems or those who use it long-term.
Br120.00
Omeprazole
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