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Cascara sagrada
Cascara Sagrada is a natural stimulant laxative derived from the bark of the Rhamnus purshiana tree.
Applications:
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Used to relieve occasional constipation.
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Sometimes included in herbal detox or colon cleanse products.
Side Effects:
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Common: abdominal cramps, diarrhea.
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Serious (with long-term use): electrolyte imbalance, dependency, liver damage (rare).
Br120.00Cascara sagrada
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Promethazine Hydrochloride
Promethazine Hydrochloride is an antihistamine with antiemetic, sedative, and anticholinergic properties.
Applications:
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Treats nausea, vomiting, and motion sickness.
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Used as a sedative or for allergy symptoms.
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Sometimes used pre/post-surgery for nausea control.
Side Effects:
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Common: drowsiness, dry mouth, dizziness.
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Serious (rare): respiratory depression (especially in children), severe tissue damage if injected improperly.
Br120.00Promethazine Hydrochloride
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Meclizine Hydrochloride
Meclizine Hydrochloride is an antihistamine used to treat motion sickness and vertigo.
Applications:
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Prevents and treats nausea, vomiting, and dizziness from motion sickness.
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Manages vertigo from inner ear disorders like Ménière’s disease.
Side Effects:
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Common: drowsiness, dry mouth, and blurred vision.
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Serious (rare): confusion, especially in older adults.
Br120.00Meclizine Hydrochloride
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00Fosaprepitant
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00Aprepitant
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Atropine Sulphate
Applications:
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Pre-Anesthesia: Reduces saliva and respiratory secretions before surgery.
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Bradycardia: Emergency treatment for abnormally slow heart rate.
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Poison Antidote: Countacts organophosphate or nerve agent poisoning.
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Ophthalmic Use: Dilates pupils for eye exams or inflammation treatment.
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GI Disorders: Relieves spasms in irritable bowel (rarely used today).
Side Effects:
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Common: Dry mouth, blurred vision, rapid heartbeat, dizziness.
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Serious:
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Hallucinations/confusion (high doses)
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Urinary retention
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Glaucoma attacks (with eye drops)
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Dangerous tachycardia (overdose)
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Note:
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IV/IM use only in emergencies (hospital/EMS).
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Reverses life-threatening cholinergic toxicity (e.g., pesticide poisoning).
Br120.00Atropine Sulphate
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Nizatidine
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and conditions related to excess stomach acid.
- Helps reduce acid production in the stomach, promoting healing and alleviating symptoms like heartburn.
Side Effects:
- Headache, dizziness, and constipation.
- In rare cases, can cause liver issues or confusion, especially in older adults.
Nizatidine is effective in managing acid-related gastrointestinal conditions, but it can cause mild side effects like headache and constipation. Serious side effects are rare but should be monitored, particularly in individuals with liver issues.
Br120.00Nizatidine
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