Applications:

• Overactive Bladder (OAB): Treats urinary frequency, urgency, and incontinence.

• Neurogenic Detrusor Overactivity: Manages bladder spasms in neurological conditions (e.g., MS, spinal injury).

Side Effects:

• Common: Dry mouth (35% of users), constipation, blurred vision, headache.

• Serious (Rare):

  • QT prolongation (caution in heart disease).

  • Angioedema (swelling of face/throat).

  • Urinary retention (risk in prostate enlargement).

Applications:

• Overactive Bladder (OAB): Reduces urgency, frequency, and incontinence.

• Neurogenic Bladder: Manages urinary leakage in spinal cord injury/MS.

• Pediatric Enuresis: Treats bedwetting (off-label in children ≥5 yrs).

Side Effects:

• Common: Dry mouth (70% of users), constipation, blurred vision, drowsiness.

• Serious (Rare):

  • Urinary retention (risk in prostate enlargement).

  • Heatstroke (reduced sweating in high temperatures).

  • CNS effects (confusion in elderly).

Applications:

• Pre-Anesthesia: Reduces saliva and respiratory secretions before surgery.

• Bradycardia: Emergency treatment for abnormally slow heart rate.

• Poison Antidote: Countacts organophosphate or nerve agent poisoning.

• Ophthalmic Use: Dilates pupils for eye exams or inflammation treatment.

• GI Disorders: Relieves spasms in irritable bowel (rarely used today).

Side Effects:

• Common: Dry mouth, blurred vision, rapid heartbeat, dizziness.

• Serious:

  • Hallucinations/confusion (high doses)

  • Urinary retention

  • Glaucoma attacks (with eye drops)

  • Dangerous tachycardia (overdose)

Note:

• IV/IM use only in emergencies (hospital/EMS).

• Reverses life-threatening cholinergic toxicity (e.g., pesticide poisoning).