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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00
Fosaprepitant
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Doxylamine succinate + Pyridoxine Hydrochloride
Doxylamine Succinate + Pyridoxine Hydrochloride is a combination used to treat nausea and vomiting during pregnancy (morning sickness).
Applications:
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First-line treatment for morning sickness in pregnant women.
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Helps reduce nausea and vomiting without harming the fetus.
Side Effects:
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Common: drowsiness, dry mouth, dizziness, and headache.
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Serious (rare): allergic reactions, confusion, and difficulty urinating.
Br120.00
Doxylamine succinate + Pyridoxine Hydrochloride
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00
Aprepitant
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Hyoscine/Scopolamine Butyl bromide
Applications:
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GI Spasms: Treats irritable bowel syndrome (IBS), diverticulitis, and abdominal cramps.
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Biliary/Urinary Colic: Relieves pain from gallstones or kidney stones.
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Endoscopic Procedures: Reduces intestinal motility during colonoscopy.
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Menstrual Cramps: Eases dysmenorrhea (off-label use).
Side Effects:
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Common: Dry mouth, dizziness, blurred vision (mild anticholinergic effects).
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Serious (Rare):
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Tachycardia (fast heart rate).
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Urinary retention (especially in elderly men with prostate issues).
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Allergic reactions (rash, anaphylaxis).
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Br120.00
Hyoscine/Scopolamine Butyl bromide
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Atropine Sulphate
Applications:
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Pre-Anesthesia: Reduces saliva and respiratory secretions before surgery.
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Bradycardia: Emergency treatment for abnormally slow heart rate.
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Poison Antidote: Countacts organophosphate or nerve agent poisoning.
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Ophthalmic Use: Dilates pupils for eye exams or inflammation treatment.
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GI Disorders: Relieves spasms in irritable bowel (rarely used today).
Side Effects:
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Common: Dry mouth, blurred vision, rapid heartbeat, dizziness.
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Serious:
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Hallucinations/confusion (high doses)
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Urinary retention
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Glaucoma attacks (with eye drops)
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Dangerous tachycardia (overdose)
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Note:
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IV/IM use only in emergencies (hospital/EMS).
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Reverses life-threatening cholinergic toxicity (e.g., pesticide poisoning).
Br120.00
Atropine Sulphate
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Omeprazole + Sodium Bicarbonate
Omeprazole + Sodium Bicarbonate is a combination used primarily for the treatment of gastroesophageal reflux disease (GERD), acid reflux, and peptic ulcers, similar to sucralfate, but it works differently.
Applications:
- Treats GERD, heartburn, and acid reflux.
- Helps heal and prevent ulcers by reducing stomach acid production.
- Used to manage Zollinger-Ellison syndrome, where excess acid is produced.
Side Effects:
- Common: headache, nausea, diarrhea, and abdominal pain.
- Rare but serious: severe allergic reactions, kidney problems, and bone fractures with long-term use.
- Prolonged use can lead to vitamin B12 deficiency and low magnesium levels.
Unlike sucralfate, which forms a protective layer over ulcers, omeprazole with sodium bicarbonate works by reducing stomach acid to help heal and prevent damage.
Br120.00
Omeprazole + Sodium Bicarbonate
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Famotidine
Applications:
- Used to treat gastroesophageal reflux disease (GERD), ulcers, and conditions caused by excess stomach acid like Zollinger-Ellison syndrome.
- Helps reduce stomach acid production to promote healing and relieve symptoms like heartburn.
Side Effects:
- Headache, dizziness, and constipation.
- In rare cases, can cause confusion, especially in older adults or those with kidney issues.
Famotidine is effective for managing acid-related digestive disorders and is generally well-tolerated. However, like any medication, it can cause side effects, especially in individuals with pre-existing kidney conditions.
Br120.00
Famotidine
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Esomeprazole
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
- Helps reduce stomach acid production, promoting healing and preventing acid-related damage.
Side Effects:
- Headache, nausea, and diarrhea.
- Long-term use may increase the risk of fractures, kidney issues, and vitamin B12 deficiency.
Esomeprazole is effective in reducing acid production, helping treat GERD and ulcers, but prolonged use can lead to some serious side effects, especially with prolonged therapy. It’s important to monitor for any complications, particularly with long-term use.
Br120.00
Esomeprazole
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