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Bisacodyl
Bisacodyl is a stimulant laxative used to treat constipation and prepare the bowel for medical procedures.
Applications:
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Relieves occasional constipation.
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Used for bowel cleansing before colonoscopy or surgery.
Side Effects:
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Common: abdominal cramps, diarrhea, nausea.
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Serious (rare): electrolyte imbalance, dehydration with prolonged use.
Br120.00Bisacodyl
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00Fosaprepitant
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Doxylamine succinate + Pyridoxine Hydrochloride
Doxylamine Succinate + Pyridoxine Hydrochloride is a combination used to treat nausea and vomiting during pregnancy (morning sickness).
Applications:
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First-line treatment for morning sickness in pregnant women.
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Helps reduce nausea and vomiting without harming the fetus.
Side Effects:
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Common: drowsiness, dry mouth, dizziness, and headache.
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Serious (rare): allergic reactions, confusion, and difficulty urinating.
Br120.00Doxylamine succinate + Pyridoxine Hydrochloride
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Chlorpromazine Hydrochloride
Applications:
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Psychosis (schizophrenia, mania)
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Severe nausea/vomiting
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Intractable hiccups
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Acute agitation/sedation
Side Effects:
Common: Drowsiness, dry mouth, constipation, low BP
Serious:-
Muscle spasms (EPS), tardive dyskinesia
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Neuroleptic malignant syndrome (NMS)
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QT prolongation → heart rhythm risk
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Seizures, confusion (elderly)
Avoid in: Glaucoma, Parkinson’s, heart rhythm issues.
Br120.00Chlorpromazine Hydrochloride
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00Aprepitant
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Drotaverine
Applications:
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Abdominal Pain: Relieves cramps in IBS, gastritis, or menstrual discomfort.
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Biliary Colic: Eases spasms in gallbladder/bile duct disorders.
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Urinary Tract Spasms: Treats discomfort from kidney stones or UTIs.
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Gynecological Use: Reduces labor pains (off-label) and dysmenorrhea.
Side Effects:
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Common: Dizziness, nausea, mild headache.
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Rare:
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Allergic reactions (rash, itching).
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Low blood pressure (with high doses).
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Rapid heartbeat (tachycardia).
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Br120.00Drotaverine
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Nizatidine
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and conditions related to excess stomach acid.
- Helps reduce acid production in the stomach, promoting healing and alleviating symptoms like heartburn.
Side Effects:
- Headache, dizziness, and constipation.
- In rare cases, can cause liver issues or confusion, especially in older adults.
Nizatidine is effective in managing acid-related gastrointestinal conditions, but it can cause mild side effects like headache and constipation. Serious side effects are rare but should be monitored, particularly in individuals with liver issues.
Br120.00Nizatidine
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Chlordiazepoxide + Clidinium Bromide.
Chlordiazepoxide + Clidinium Bromide:
Applications:
- Used to treat irritable bowel syndrome (IBS) and other gastrointestinal disorders with spasm or pain.
- Helps manage anxiety and agitation associated with gastrointestinal conditions.
Side Effects:
- Drowsiness, dizziness, and blurred vision.
- Dry mouth, constipation, and urinary retention.
This combination helps reduce symptoms of both gastrointestinal discomfort and anxiety, though it can cause sedation and other common side effects like dry mouth. Be cautious when operating machinery or driving.
Br120.00Chlordiazepoxide + Clidinium Bromide.
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