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Bisacodyl
Bisacodyl is a stimulant laxative used to treat constipation and prepare the bowel for medical procedures.
Applications:
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Relieves occasional constipation.
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Used for bowel cleansing before colonoscopy or surgery.
Side Effects:
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Common: abdominal cramps, diarrhea, nausea.
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Serious (rare): electrolyte imbalance, dehydration with prolonged use.
Br120.00
Bisacodyl
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Meclizine Hydrochloride
Meclizine Hydrochloride is an antihistamine used to treat motion sickness and vertigo.
Applications:
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Prevents and treats nausea, vomiting, and dizziness from motion sickness.
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Manages vertigo from inner ear disorders like Ménière’s disease.
Side Effects:
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Common: drowsiness, dry mouth, and blurred vision.
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Serious (rare): confusion, especially in older adults.
Br120.00
Meclizine Hydrochloride
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00
Fosaprepitant
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00
Aprepitant
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Tolterodine
Applications:
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Overactive Bladder (OAB): Treats urinary frequency, urgency, and incontinence.
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Neurogenic Detrusor Overactivity: Manages bladder spasms in neurological conditions (e.g., MS, spinal injury).
Side Effects:
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Common: Dry mouth (35% of users), constipation, blurred vision, headache.
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Serious (Rare):
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QT prolongation (caution in heart disease).
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Angioedema (swelling of face/throat).
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Urinary retention (risk in prostate enlargement).
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Br120.00
Tolterodine
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Darifenacin
Applications:
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Overactive Bladder (OAB): Treats frequent urination, urgency, and incontinence.
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Neurogenic Detrusor Overactivity: Manages bladder control issues in neurological conditions (e.g., MS, spinal cord injury).
Side Effects:
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Common: Dry mouth, constipation, blurred vision, dizziness.
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Serious (Rare):
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Severe allergic reactions (rash, swelling).
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Worsening glaucoma (caution in patients with eye conditions).
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Urinary retention (in men with prostate enlargement).
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Br120.00
Darifenacin
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Ranitidine
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and conditions where the stomach produces too much acid (like Zollinger-Ellison syndrome).
- Reduces stomach acid production, helping to heal ulcers and manage heartburn or acid reflux.
- Can be used for the prevention and treatment of ulcers and conditions like indigestion.
Side Effects:
- Common side effects include headache, dizziness, constipation, or diarrhea.
- Rare but serious side effects may include liver problems, irregular heartbeats, and severe allergic reactions.
- Long-term use can occasionally lead to vitamin B12 deficiency.
Ranitidine is effective in controlling excess stomach acid but was withdrawn from many markets (including the U.S.) in 2020 due to concerns over a potential carcinogenic impurity. For those still using it, monitoring for side effects is important, especially if taken for prolonged periods.
Br120.00
Ranitidine
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