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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00Fosaprepitant
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Domperidone
Domperidone is a dopamine antagonist used to treat nausea, vomiting, and gastrointestinal motility disorders.
Applications:
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Relieves nausea and vomiting.
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Treats gastroparesis by enhancing stomach emptying.
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Sometimes used to increase breast milk production (off-label).
Side Effects:
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Common: dry mouth, abdominal cramps, and headache.
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Serious (rare): heart rhythm disorders, especially in elderly or high doses.
Br120.00Domperidone
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00Aprepitant
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Tolterodine
Applications:
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Overactive Bladder (OAB): Treats urinary frequency, urgency, and incontinence.
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Neurogenic Detrusor Overactivity: Manages bladder spasms in neurological conditions (e.g., MS, spinal injury).
Side Effects:
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Common: Dry mouth (35% of users), constipation, blurred vision, headache.
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Serious (Rare):
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QT prolongation (caution in heart disease).
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Angioedema (swelling of face/throat).
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Urinary retention (risk in prostate enlargement).
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Br120.00Tolterodine
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Sucralfate
Sure! Here’s a similar overview for sucralfate:
Applications:
- Used primarily to treat and prevent peptic ulcers by forming a protective barrier over ulcer sites in the stomach and intestines.
- Often prescribed for gastroesophageal reflux disease (GERD) and to manage conditions involving damage to the stomach lining, like gastritis.
- Can help in the healing of esophageal ulcers, as well as ulcers caused by nonsteroidal anti-inflammatory drugs (NSAIDs).
Side Effects:
- Common side effects include constipation, dry mouth, and mild stomach discomfort.
- Rare but serious side effects can include allergic reactions, severe abdominal pain, or difficulty breathing.
- Prolonged use may lead to malabsorption of nutrients like phosphate, which can cause low phosphate levels.
- In some cases, patients may experience dizziness or headache.
Sucralfate is typically considered a safe treatment, but like with any medication, it’s important to monitor for any adverse effects, particularly with long-term use.
Br120.00Sucralfate
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Esomeprazole
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
- Helps reduce stomach acid production, promoting healing and preventing acid-related damage.
Side Effects:
- Headache, nausea, and diarrhea.
- Long-term use may increase the risk of fractures, kidney issues, and vitamin B12 deficiency.
Esomeprazole is effective in reducing acid production, helping treat GERD and ulcers, but prolonged use can lead to some serious side effects, especially with prolonged therapy. It’s important to monitor for any complications, particularly with long-term use.
Br120.00Esomeprazole
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