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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00
Fosaprepitant
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00
Aprepitant
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Simethicone + Algerines citrate
Applications:
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Bloating & Gas Relief:
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Simethicone: Breaks down gas bubbles in the gut (anti-foaming agent).
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Alverine Citrate: Relieves intestinal spasms (smooth muscle relaxant).
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Irritable Bowel Syndrome (IBS): Reduces cramping, distension, and discomfort.
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Functional GI Disorders: Eases symptoms of dyspepsia or diverticular disease.
Side Effects:
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Simethicone: Generally side-effect-free (not absorbed systemically).
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Alverine Citrate:
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Mild: Dizziness, nausea, headache.
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Rare: Allergic reactions (rash, itching).
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Br120.00
Simethicone + Algerines citrate
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Hyoscine/Scopolamine Butyl bromide
Applications:
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GI Spasms: Treats irritable bowel syndrome (IBS), diverticulitis, and abdominal cramps.
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Biliary/Urinary Colic: Relieves pain from gallstones or kidney stones.
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Endoscopic Procedures: Reduces intestinal motility during colonoscopy.
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Menstrual Cramps: Eases dysmenorrhea (off-label use).
Side Effects:
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Common: Dry mouth, dizziness, blurred vision (mild anticholinergic effects).
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Serious (Rare):
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Tachycardia (fast heart rate).
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Urinary retention (especially in elderly men with prostate issues).
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Allergic reactions (rash, anaphylaxis).
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Br120.00
Hyoscine/Scopolamine Butyl bromide
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Propranolol
Applications:
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Heart: Treats high BP, angina, arrhythmias, prevents heart attacks
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Migraines: Reduces frequency
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Anxiety: Controls physical symptoms (shaking, fast heartbeat)
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Hyperthyroidism: Manages symptoms like rapid pulse
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Essential tremor: Decreases shaking
Side Effects:
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Common: Fatigue, dizziness, cold hands/feet, sleep issues
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Serious (rare):
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Slow heart rate, wheezing (caution in asthma patients)
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Worsening heart failure, depression
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Note:
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Avoid sudden stoppage (taper gradually).
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Brands: Inderal®, Hemangeol®, generics.
Monitor heart rate & BP. Not for asthma/COPD patients.
Br120.00
Propranolol
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Octreotide
Applications:
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Treats acromegaly (reduces growth hormone)
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Manages neuroendocrine tumors (controls carcinoid/VIPoma symptoms)
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Stops severe GI bleeding (esophageal varices, ulcers)
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Closes pancreatic/intestinal fistulas
Side Effects:
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Common: Nausea, diarrhea, gallstones, blood sugar changes
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Serious (rare): Heart rhythm issues, thyroid dysfunction
Note: Requires monitoring for gallbladder and metabolic effects. Available in short-acting (daily) and long-acting (monthly) forms.
Br120.00
Octreotide
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Omeprazole + Sodium Bicarbonate
Omeprazole + Sodium Bicarbonate is a combination used primarily for the treatment of gastroesophageal reflux disease (GERD), acid reflux, and peptic ulcers, similar to sucralfate, but it works differently.
Applications:
- Treats GERD, heartburn, and acid reflux.
- Helps heal and prevent ulcers by reducing stomach acid production.
- Used to manage Zollinger-Ellison syndrome, where excess acid is produced.
Side Effects:
- Common: headache, nausea, diarrhea, and abdominal pain.
- Rare but serious: severe allergic reactions, kidney problems, and bone fractures with long-term use.
- Prolonged use can lead to vitamin B12 deficiency and low magnesium levels.
Unlike sucralfate, which forms a protective layer over ulcers, omeprazole with sodium bicarbonate works by reducing stomach acid to help heal and prevent damage.
Br120.00
Omeprazole + Sodium Bicarbonate
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Sucralfate
Sure! Here’s a similar overview for sucralfate:
Applications:
- Used primarily to treat and prevent peptic ulcers by forming a protective barrier over ulcer sites in the stomach and intestines.
- Often prescribed for gastroesophageal reflux disease (GERD) and to manage conditions involving damage to the stomach lining, like gastritis.
- Can help in the healing of esophageal ulcers, as well as ulcers caused by nonsteroidal anti-inflammatory drugs (NSAIDs).
Side Effects:
- Common side effects include constipation, dry mouth, and mild stomach discomfort.
- Rare but serious side effects can include allergic reactions, severe abdominal pain, or difficulty breathing.
- Prolonged use may lead to malabsorption of nutrients like phosphate, which can cause low phosphate levels.
- In some cases, patients may experience dizziness or headache.
Sucralfate is typically considered a safe treatment, but like with any medication, it’s important to monitor for any adverse effects, particularly with long-term use.
Br120.00
Sucralfate
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