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Palonosetron Hydrochloride
Palonosetron Hydrochloride is a long-acting 5-HT3 receptor antagonist used to prevent nausea and vomiting.
Applications:
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Prevents acute and delayed nausea/vomiting from moderately to highly emetogenic chemotherapy.
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Also used for postoperative nausea and vomiting.
Side Effects:
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Common: headache, constipation, dizziness.
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Serious (rare): QT prolongation, hypersensitivity reactions.
Br120.00Palonosetron Hydrochloride
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00Fosaprepitant
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00Aprepitant
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Oxybutynin
Applications:
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Overactive Bladder (OAB): Reduces urgency, frequency, and incontinence.
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Neurogenic Bladder: Manages urinary leakage in spinal cord injury/MS.
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Pediatric Enuresis: Treats bedwetting (off-label in children ≥5 yrs).
Side Effects:
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Common: Dry mouth (70% of users), constipation, blurred vision, drowsiness.
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Serious (Rare):
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Urinary retention (risk in prostate enlargement).
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Heatstroke (reduced sweating in high temperatures).
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CNS effects (confusion in elderly).
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Br120.00Oxybutynin
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Mebeverine
Applications:
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Irritable Bowel Syndrome (IBS): Relieves abdominal pain, bloating, and cramps.
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Functional GI Disorders: Manages spasms in conditions like diverticulitis.
Side Effects:
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Common: Mild dizziness, headache, nausea.
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Rare:
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Allergic reactions (rash, itching).
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Constipation or diarrhea.
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Br120.00Mebeverine
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Atropine Sulphate
Applications:
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Pre-Anesthesia: Reduces saliva and respiratory secretions before surgery.
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Bradycardia: Emergency treatment for abnormally slow heart rate.
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Poison Antidote: Countacts organophosphate or nerve agent poisoning.
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Ophthalmic Use: Dilates pupils for eye exams or inflammation treatment.
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GI Disorders: Relieves spasms in irritable bowel (rarely used today).
Side Effects:
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Common: Dry mouth, blurred vision, rapid heartbeat, dizziness.
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Serious:
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Hallucinations/confusion (high doses)
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Urinary retention
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Glaucoma attacks (with eye drops)
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Dangerous tachycardia (overdose)
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Note:
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IV/IM use only in emergencies (hospital/EMS).
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Reverses life-threatening cholinergic toxicity (e.g., pesticide poisoning).
Br120.00Atropine Sulphate
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Sucralfate
Sure! Here’s a similar overview for sucralfate:
Applications:
- Used primarily to treat and prevent peptic ulcers by forming a protective barrier over ulcer sites in the stomach and intestines.
- Often prescribed for gastroesophageal reflux disease (GERD) and to manage conditions involving damage to the stomach lining, like gastritis.
- Can help in the healing of esophageal ulcers, as well as ulcers caused by nonsteroidal anti-inflammatory drugs (NSAIDs).
Side Effects:
- Common side effects include constipation, dry mouth, and mild stomach discomfort.
- Rare but serious side effects can include allergic reactions, severe abdominal pain, or difficulty breathing.
- Prolonged use may lead to malabsorption of nutrients like phosphate, which can cause low phosphate levels.
- In some cases, patients may experience dizziness or headache.
Sucralfate is typically considered a safe treatment, but like with any medication, it’s important to monitor for any adverse effects, particularly with long-term use.
Br120.00Sucralfate
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Moov Fast Pain Relief Cream
- Unrestrained and portable active stereo speaker
- Free from the confines of wires and chords
- 20 hours of portable capabilities
- Double-ended Coil Cord with 3.5mm Stereo Plugs Included
- 3/4″ Dome Tweeters: 2X and 4″ Woofer: 1X
Br625.50Br822.70 -
Moov Fast Pain Relief Cream
- Unrestrained and portable active stereo speaker
- Free from the confines of wires and chords
- 20 hours of portable capabilities
- Double-ended Coil Cord with 3.5mm Stereo Plugs Included
- 3/4″ Dome Tweeters: 2X and 4″ Woofer: 1X
Br625.50Br822.70