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Palonosetron Hydrochloride
Palonosetron Hydrochloride is a long-acting 5-HT3 receptor antagonist used to prevent nausea and vomiting.
Applications:
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Prevents acute and delayed nausea/vomiting from moderately to highly emetogenic chemotherapy.
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Also used for postoperative nausea and vomiting.
Side Effects:
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Common: headache, constipation, dizziness.
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Serious (rare): QT prolongation, hypersensitivity reactions.
Br120.00Palonosetron Hydrochloride
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Hyoscine/Scopolamine Hydrobromide
Hyoscine/Scopolamine Hydrobromide is an anticholinergic used to prevent motion sickness and treat nausea.
Applications:
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Prevents motion sickness-related nausea and vomiting.
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Used for postoperative nausea and in palliative care to reduce secretions.
Side Effects:
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Common: dry mouth, drowsiness, blurred vision, and dizziness.
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Serious (rare): confusion, hallucinations, and urinary retention.
Br120.00Hyoscine/Scopolamine Hydrobromide
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Dimenhydrinate
Dimenhydrinate is an antihistamine primarily used to prevent and treat motion sickness and nausea.
Applications:
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Prevents and relieves nausea, vomiting, and dizziness from motion sickness.
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Used for vertigo and inner ear disturbances like Ménière’s disease.
Side Effects:
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Common: drowsiness, dry mouth, dizziness, and blurred vision.
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Serious (rare): confusion (especially in elderly), fast heartbeat, and urinary retention.
Br120.00Dimenhydrinate
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Tolterodine
Applications:
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Overactive Bladder (OAB): Treats urinary frequency, urgency, and incontinence.
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Neurogenic Detrusor Overactivity: Manages bladder spasms in neurological conditions (e.g., MS, spinal injury).
Side Effects:
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Common: Dry mouth (35% of users), constipation, blurred vision, headache.
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Serious (Rare):
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QT prolongation (caution in heart disease).
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Angioedema (swelling of face/throat).
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Urinary retention (risk in prostate enlargement).
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Br120.00Tolterodine
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Oxybutynin
Applications:
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Overactive Bladder (OAB): Reduces urgency, frequency, and incontinence.
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Neurogenic Bladder: Manages urinary leakage in spinal cord injury/MS.
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Pediatric Enuresis: Treats bedwetting (off-label in children ≥5 yrs).
Side Effects:
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Common: Dry mouth (70% of users), constipation, blurred vision, drowsiness.
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Serious (Rare):
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Urinary retention (risk in prostate enlargement).
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Heatstroke (reduced sweating in high temperatures).
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CNS effects (confusion in elderly).
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Br120.00Oxybutynin
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Hyoscine/Scopolamine Butyl bromide
Applications:
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GI Spasms: Treats irritable bowel syndrome (IBS), diverticulitis, and abdominal cramps.
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Biliary/Urinary Colic: Relieves pain from gallstones or kidney stones.
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Endoscopic Procedures: Reduces intestinal motility during colonoscopy.
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Menstrual Cramps: Eases dysmenorrhea (off-label use).
Side Effects:
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Common: Dry mouth, dizziness, blurred vision (mild anticholinergic effects).
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Serious (Rare):
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Tachycardia (fast heart rate).
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Urinary retention (especially in elderly men with prostate issues).
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Allergic reactions (rash, anaphylaxis).
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Br120.00Hyoscine/Scopolamine Butyl bromide
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Ranitidine
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and conditions where the stomach produces too much acid (like Zollinger-Ellison syndrome).
- Reduces stomach acid production, helping to heal ulcers and manage heartburn or acid reflux.
- Can be used for the prevention and treatment of ulcers and conditions like indigestion.
Side Effects:
- Common side effects include headache, dizziness, constipation, or diarrhea.
- Rare but serious side effects may include liver problems, irregular heartbeats, and severe allergic reactions.
- Long-term use can occasionally lead to vitamin B12 deficiency.
Ranitidine is effective in controlling excess stomach acid but was withdrawn from many markets (including the U.S.) in 2020 due to concerns over a potential carcinogenic impurity. For those still using it, monitoring for side effects is important, especially if taken for prolonged periods.
Br120.00Ranitidine
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