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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00Fosaprepitant
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Domperidone
Domperidone is a dopamine antagonist used to treat nausea, vomiting, and gastrointestinal motility disorders.
Applications:
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Relieves nausea and vomiting.
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Treats gastroparesis by enhancing stomach emptying.
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Sometimes used to increase breast milk production (off-label).
Side Effects:
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Common: dry mouth, abdominal cramps, and headache.
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Serious (rare): heart rhythm disorders, especially in elderly or high doses.
Br120.00Domperidone
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00Aprepitant
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Rabeprazole sodium
Applications:
- Used to treat gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers.
- Reduces stomach acid, promoting healing of the esophagus and ulcers.
- Effective in treating Zollinger-Ellison syndrome (excessive acid production).
Side Effects:
- Common side effects include headache, diarrhea, nausea, and abdominal pain.
- Rare side effects include low magnesium levels, bone fractures, and kidney issues, especially with prolonged use.
Rabeprazole sodium is a helpful treatment for acid-related gastrointestinal issues but, like other proton pump inhibitors, may lead to mild side effects such as headaches or stomach discomfort. Serious side effects are uncommon but should be monitored, especially during long-term use or in individuals with kidney concerns.
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Esomeprazole
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
- Helps reduce stomach acid production, promoting healing and preventing acid-related damage.
Side Effects:
- Headache, nausea, and diarrhea.
- Long-term use may increase the risk of fractures, kidney issues, and vitamin B12 deficiency.
Esomeprazole is effective in reducing acid production, helping treat GERD and ulcers, but prolonged use can lead to some serious side effects, especially with prolonged therapy. It’s important to monitor for any complications, particularly with long-term use.
Br120.00Esomeprazole
Br120.00 Select options This product has multiple variants. The options may be chosen on the product page