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    Fosaprepitant

    Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.

    Applications:

    • Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.

    • Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).

    Side Effects:

    • Common: fatigue, headache, hiccups, and constipation.

    • Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.

    Brands: Emend (IV).

    Br120.00
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    Fosaprepitant

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    Domperidone

    Domperidone is a dopamine antagonist used to treat nausea, vomiting, and gastrointestinal motility disorders.

    Applications:

    • Relieves nausea and vomiting.

    • Treats gastroparesis by enhancing stomach emptying.

    • Sometimes used to increase breast milk production (off-label).

    Side Effects:

    • Common: dry mouth, abdominal cramps, and headache.

    • Serious (rare): heart rhythm disorders, especially in elderly or high doses.

    Br120.00
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    Domperidone

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    Chlorpromazine Hydrochloride

    Applications:

    • Psychosis (schizophrenia, mania)

    • Severe nausea/vomiting

    • Intractable hiccups

    • Acute agitation/sedation

    Side Effects:

    Common: Drowsiness, dry mouth, constipation, low BP
    Serious:

    • Muscle spasms (EPS), tardive dyskinesia

    • Neuroleptic malignant syndrome (NMS)

    • QT prolongation → heart rhythm risk

    • Seizures, confusion (elderly)

    Avoid in: Glaucoma, Parkinson’s, heart rhythm issues.

    Br120.00
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    Chlorpromazine Hydrochloride

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    Aprepitant

    Applications:

    Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
    Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
    Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).

    Side Effects:

    Common: Fatigue, hiccups, constipation, headache, loss of appetite.
    Serious (Rare):

    • Liver toxicity (elevated LFTs).

    • Hypersensitivity (rash, anaphylaxis).

    • Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).

    Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.

    Br120.00
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    Aprepitant

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    Tolterodine

    Applications:

    • Overactive Bladder (OAB): Treats urinary frequency, urgency, and incontinence.

    • Neurogenic Detrusor Overactivity: Manages bladder spasms in neurological conditions (e.g., MS, spinal injury).

    Side Effects:

    • Common: Dry mouth (35% of users), constipation, blurred vision, headache.

    • Serious (Rare):

      • QT prolongation (caution in heart disease).

      • Angioedema (swelling of face/throat).

      • Urinary retention (risk in prostate enlargement).

    Br120.00
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    Tolterodine

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    Propantheline Bromide

    Applications:

    • Peptic Ulcers: Reduces gastric acid secretion (adjunct therapy).

    • Hyperhidrosis: Controls excessive sweating (off-label).

    • GI Spasms: Manages irritable bowel syndrome (IBS) and diverticulitis.

    • Urinary Incontinence: Treats overactive bladder (less common now).

    Side Effects:

    • Common: Dry mouth, blurred vision, constipation, drowsiness.

    • Serious (Rare):

      • Urinary retention (risk in prostate enlargement).

      • Tachycardia (fast heart rate).

      • Glaucoma exacerbation (avoid in narrow-angle glaucoma).

    Br120.00
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    Propantheline Bromide

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    Famotidine

    Applications:

    • Used to treat gastroesophageal reflux disease (GERD), ulcers, and conditions caused by excess stomach acid like Zollinger-Ellison syndrome.
    • Helps reduce stomach acid production to promote healing and relieve symptoms like heartburn.

    Side Effects:

    • Headache, dizziness, and constipation.
    • In rare cases, can cause confusion, especially in older adults or those with kidney issues.

    Famotidine is effective for managing acid-related digestive disorders and is generally well-tolerated. However, like any medication, it can cause side effects, especially in individuals with pre-existing kidney conditions.

    Br120.00
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    Famotidine

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