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Lactulose
Lactulose is an osmotic laxative used to treat constipation and manage hepatic encephalopathy.
Applications:
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Relieves chronic constipation by drawing water into the bowel.
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Reduces blood ammonia levels in patients with liver disease (hepatic encephalopathy).
Side Effects:
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Common: bloating, gas, abdominal cramps, diarrhea.
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Serious (rare): electrolyte imbalance with prolonged use or high doses.
Br120.00Lactulose
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Hyoscine/Scopolamine Hydrobromide
Hyoscine/Scopolamine Hydrobromide is an anticholinergic used to prevent motion sickness and treat nausea.
Applications:
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Prevents motion sickness-related nausea and vomiting.
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Used for postoperative nausea and in palliative care to reduce secretions.
Side Effects:
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Common: dry mouth, drowsiness, blurred vision, and dizziness.
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Serious (rare): confusion, hallucinations, and urinary retention.
Br120.00Hyoscine/Scopolamine Hydrobromide
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00Fosaprepitant
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00Aprepitant
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Omeprazole
Applications:
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Treats severe GERD/ulcers (when oral therapy fails)
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Manages Zollinger-Ellison syndrome (acid hypersecretion)
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Prevents acid aspiration during surgery
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Reduces rebleeding risk after endoscopic treatment
Side Effects:
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Common: Headache, nausea, injection-site pain
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Serious (rare): Kidney injury, low magnesium, bone fractures (long-term use)
Note: Requires kidney/magnesium monitoring with prolonged IV use. Administered once daily (40mg). Brands include Losec® IV and generics.
Br120.00Omeprazole
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Nizatidine
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and conditions related to excess stomach acid.
- Helps reduce acid production in the stomach, promoting healing and alleviating symptoms like heartburn.
Side Effects:
- Headache, dizziness, and constipation.
- In rare cases, can cause liver issues or confusion, especially in older adults.
Nizatidine is effective in managing acid-related gastrointestinal conditions, but it can cause mild side effects like headache and constipation. Serious side effects are rare but should be monitored, particularly in individuals with liver issues.
Br120.00Nizatidine
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