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Lactulose
Lactulose is an osmotic laxative used to treat constipation and manage hepatic encephalopathy.
Applications:
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Relieves chronic constipation by drawing water into the bowel.
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Reduces blood ammonia levels in patients with liver disease (hepatic encephalopathy).
Side Effects:
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Common: bloating, gas, abdominal cramps, diarrhea.
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Serious (rare): electrolyte imbalance with prolonged use or high doses.
Br120.00
Lactulose
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Bisacodyl
Bisacodyl is a stimulant laxative used to treat constipation and prepare the bowel for medical procedures.
Applications:
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Relieves occasional constipation.
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Used for bowel cleansing before colonoscopy or surgery.
Side Effects:
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Common: abdominal cramps, diarrhea, nausea.
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Serious (rare): electrolyte imbalance, dehydration with prolonged use.
Br120.00
Bisacodyl
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Palonosetron Hydrochloride
Palonosetron Hydrochloride is a long-acting 5-HT3 receptor antagonist used to prevent nausea and vomiting.
Applications:
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Prevents acute and delayed nausea/vomiting from moderately to highly emetogenic chemotherapy.
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Also used for postoperative nausea and vomiting.
Side Effects:
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Common: headache, constipation, dizziness.
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Serious (rare): QT prolongation, hypersensitivity reactions.
Br120.00
Palonosetron Hydrochloride
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Metoclopramide Hydrochloride
Metoclopramide Hydrochloride is a dopamine antagonist used to treat nausea, vomiting, and delayed gastric emptying.
Applications:
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Treats nausea and vomiting from various causes, including chemotherapy and migraines.
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Manages gastroparesis by enhancing stomach motility.
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Used for GERD when other treatments fail.
Side Effects:
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Common: drowsiness, fatigue, restlessness.
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Serious (rare): tardive dyskinesia (involuntary movements), Parkinson-like symptoms, depression.
Br120.00
Metoclopramide Hydrochloride
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00
Fosaprepitant
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00
Aprepitant
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Tolterodine
Applications:
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Overactive Bladder (OAB): Treats urinary frequency, urgency, and incontinence.
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Neurogenic Detrusor Overactivity: Manages bladder spasms in neurological conditions (e.g., MS, spinal injury).
Side Effects:
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Common: Dry mouth (35% of users), constipation, blurred vision, headache.
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Serious (Rare):
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QT prolongation (caution in heart disease).
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Angioedema (swelling of face/throat).
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Urinary retention (risk in prostate enlargement).
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Br120.00
Tolterodine
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Chlordiazepoxide + Clidinium Bromide.
Chlordiazepoxide + Clidinium Bromide:
Applications:
- Used to treat irritable bowel syndrome (IBS) and other gastrointestinal disorders with spasm or pain.
- Helps manage anxiety and agitation associated with gastrointestinal conditions.
Side Effects:
- Drowsiness, dizziness, and blurred vision.
- Dry mouth, constipation, and urinary retention.
This combination helps reduce symptoms of both gastrointestinal discomfort and anxiety, though it can cause sedation and other common side effects like dry mouth. Be cautious when operating machinery or driving.
Br120.00
Chlordiazepoxide + Clidinium Bromide.
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