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    Promethazine Hydrochloride

    Promethazine Hydrochloride is an antihistamine with antiemetic, sedative, and anticholinergic properties.

    Applications:

    • Treats nausea, vomiting, and motion sickness.

    • Used as a sedative or for allergy symptoms.

    • Sometimes used pre/post-surgery for nausea control.

    Side Effects:

    • Common: drowsiness, dry mouth, dizziness.

    • Serious (rare): respiratory depression (especially in children), severe tissue damage if injected improperly.

    Br120.00
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    Promethazine Hydrochloride

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    Fosaprepitant

    Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.

    Applications:

    • Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.

    • Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).

    Side Effects:

    • Common: fatigue, headache, hiccups, and constipation.

    • Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.

    Brands: Emend (IV).

    Br120.00
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    Fosaprepitant

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    Chlorpromazine Hydrochloride

    Applications:

    • Psychosis (schizophrenia, mania)

    • Severe nausea/vomiting

    • Intractable hiccups

    • Acute agitation/sedation

    Side Effects:

    Common: Drowsiness, dry mouth, constipation, low BP
    Serious:

    • Muscle spasms (EPS), tardive dyskinesia

    • Neuroleptic malignant syndrome (NMS)

    • QT prolongation → heart rhythm risk

    • Seizures, confusion (elderly)

    Avoid in: Glaucoma, Parkinson’s, heart rhythm issues.

    Br120.00
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    Chlorpromazine Hydrochloride

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    Aprepitant

    Applications:

    Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
    Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
    Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).

    Side Effects:

    Common: Fatigue, hiccups, constipation, headache, loss of appetite.
    Serious (Rare):

    • Liver toxicity (elevated LFTs).

    • Hypersensitivity (rash, anaphylaxis).

    • Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).

    Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.

    Br120.00
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    Aprepitant

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