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    Promethazine Hydrochloride

    Promethazine Hydrochloride is an antihistamine with antiemetic, sedative, and anticholinergic properties.

    Applications:

    • Treats nausea, vomiting, and motion sickness.

    • Used as a sedative or for allergy symptoms.

    • Sometimes used pre/post-surgery for nausea control.

    Side Effects:

    • Common: drowsiness, dry mouth, dizziness.

    • Serious (rare): respiratory depression (especially in children), severe tissue damage if injected improperly.

    Br120.00
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    Promethazine Hydrochloride

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    Metoclopramide Hydrochloride

    Metoclopramide Hydrochloride is a dopamine antagonist used to treat nausea, vomiting, and delayed gastric emptying.

    Applications:

    • Treats nausea and vomiting from various causes, including chemotherapy and migraines.

    • Manages gastroparesis by enhancing stomach motility.

    • Used for GERD when other treatments fail.

    Side Effects:

    • Common: drowsiness, fatigue, restlessness.

    • Serious (rare): tardive dyskinesia (involuntary movements), Parkinson-like symptoms, depression.

    Br120.00
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    Metoclopramide Hydrochloride

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    Fosaprepitant

    Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.

    Applications:

    • Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.

    • Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).

    Side Effects:

    • Common: fatigue, headache, hiccups, and constipation.

    • Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.

    Brands: Emend (IV).

    Br120.00
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    Fosaprepitant

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    Dexamethasone

    Dexamethasone is a corticosteroid used to reduce inflammation and suppress the immune system.

    Applications:

    • Treats inflammatory conditions like arthritis, allergies, and skin diseases.

    • Used in cancer therapy and autoimmune disorders.

    • Helps manage cerebral edema and severe COVID-19 symptoms.

    Side Effects:

    • Common: insomnia, mood changes, increased appetite, and weight gain.

    • Serious (long-term use): osteoporosis, high blood sugar, increased infection risk, and adrenal suppression.

    Brands: Decadron, DexPak, Ozurdex (eye implant), Maxidex (eye drops).

    Br120.00
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    Dexamethasone

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    Aprepitant

    Applications:

    Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
    Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
    Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).

    Side Effects:

    Common: Fatigue, hiccups, constipation, headache, loss of appetite.
    Serious (Rare):

    • Liver toxicity (elevated LFTs).

    • Hypersensitivity (rash, anaphylaxis).

    • Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).

    Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.

    Br120.00
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    Aprepitant

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