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Metoclopramide Hydrochloride
Metoclopramide Hydrochloride is a dopamine antagonist used to treat nausea, vomiting, and delayed gastric emptying.
Applications:
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Treats nausea and vomiting from various causes, including chemotherapy and migraines.
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Manages gastroparesis by enhancing stomach motility.
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Used for GERD when other treatments fail.
Side Effects:
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Common: drowsiness, fatigue, restlessness.
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Serious (rare): tardive dyskinesia (involuntary movements), Parkinson-like symptoms, depression.
Br120.00
Metoclopramide Hydrochloride
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Meclizine Hydrochloride
Meclizine Hydrochloride is an antihistamine used to treat motion sickness and vertigo.
Applications:
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Prevents and treats nausea, vomiting, and dizziness from motion sickness.
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Manages vertigo from inner ear disorders like Ménière’s disease.
Side Effects:
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Common: drowsiness, dry mouth, and blurred vision.
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Serious (rare): confusion, especially in older adults.
Br120.00
Meclizine Hydrochloride
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00
Fosaprepitant
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00
Aprepitant
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Oxybutynin
Applications:
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Overactive Bladder (OAB): Reduces urgency, frequency, and incontinence.
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Neurogenic Bladder: Manages urinary leakage in spinal cord injury/MS.
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Pediatric Enuresis: Treats bedwetting (off-label in children ≥5 yrs).
Side Effects:
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Common: Dry mouth (70% of users), constipation, blurred vision, drowsiness.
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Serious (Rare):
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Urinary retention (risk in prostate enlargement).
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Heatstroke (reduced sweating in high temperatures).
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CNS effects (confusion in elderly).
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Br120.00
Oxybutynin
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Propranolol
Applications:
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Heart: Treats high BP, angina, arrhythmias, prevents heart attacks
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Migraines: Reduces frequency
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Anxiety: Controls physical symptoms (shaking, fast heartbeat)
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Hyperthyroidism: Manages symptoms like rapid pulse
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Essential tremor: Decreases shaking
Side Effects:
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Common: Fatigue, dizziness, cold hands/feet, sleep issues
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Serious (rare):
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Slow heart rate, wheezing (caution in asthma patients)
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Worsening heart failure, depression
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Note:
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Avoid sudden stoppage (taper gradually).
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Brands: Inderal®, Hemangeol®, generics.
Monitor heart rate & BP. Not for asthma/COPD patients.
Br120.00
Propranolol
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Omeprazole + Sodium Bicarbonate
Omeprazole + Sodium Bicarbonate is a combination used primarily for the treatment of gastroesophageal reflux disease (GERD), acid reflux, and peptic ulcers, similar to sucralfate, but it works differently.
Applications:
- Treats GERD, heartburn, and acid reflux.
- Helps heal and prevent ulcers by reducing stomach acid production.
- Used to manage Zollinger-Ellison syndrome, where excess acid is produced.
Side Effects:
- Common: headache, nausea, diarrhea, and abdominal pain.
- Rare but serious: severe allergic reactions, kidney problems, and bone fractures with long-term use.
- Prolonged use can lead to vitamin B12 deficiency and low magnesium levels.
Unlike sucralfate, which forms a protective layer over ulcers, omeprazole with sodium bicarbonate works by reducing stomach acid to help heal and prevent damage.
Br120.00
Omeprazole + Sodium Bicarbonate
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Esomeprazole
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
- Helps reduce stomach acid production, promoting healing and preventing acid-related damage.
Side Effects:
- Headache, nausea, and diarrhea.
- Long-term use may increase the risk of fractures, kidney issues, and vitamin B12 deficiency.
Esomeprazole is effective in reducing acid production, helping treat GERD and ulcers, but prolonged use can lead to some serious side effects, especially with prolonged therapy. It’s important to monitor for any complications, particularly with long-term use.
Br120.00
Esomeprazole
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