• Fosaprepitant

    Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.

    Applications:

    • Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.

    • Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).

    Side Effects:

    • Common: fatigue, headache, hiccups, and constipation.

    • Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.

    Brands: Emend (IV).

    Br120.00

    Fosaprepitant

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  • Chlorpromazine Hydrochloride

    Applications:

    • Psychosis (schizophrenia, mania)

    • Severe nausea/vomiting

    • Intractable hiccups

    • Acute agitation/sedation

    Side Effects:

    Common: Drowsiness, dry mouth, constipation, low BP
    Serious:

    • Muscle spasms (EPS), tardive dyskinesia

    • Neuroleptic malignant syndrome (NMS)

    • QT prolongation → heart rhythm risk

    • Seizures, confusion (elderly)

    Avoid in: Glaucoma, Parkinson’s, heart rhythm issues.

    Br120.00

    Chlorpromazine Hydrochloride

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  • Aprepitant

    Applications:

    Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
    Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
    Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).

    Side Effects:

    Common: Fatigue, hiccups, constipation, headache, loss of appetite.
    Serious (Rare):

    • Liver toxicity (elevated LFTs).

    • Hypersensitivity (rash, anaphylaxis).

    • Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).

    Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.

    Br120.00

    Aprepitant

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  • Mebeverine

    Applications:

    • Irritable Bowel Syndrome (IBS): Relieves abdominal pain, bloating, and cramps.

    • Functional GI Disorders: Manages spasms in conditions like diverticulitis.

    Side Effects:

    • Common: Mild dizziness, headache, nausea.

    • Rare:

      • Allergic reactions (rash, itching).

      • Constipation or diarrhea.

    Br120.00

    Mebeverine

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  • Drotaverine

    Applications:

    • Abdominal Pain: Relieves cramps in IBS, gastritis, or menstrual discomfort.

    • Biliary Colic: Eases spasms in gallbladder/bile duct disorders.

    • Urinary Tract Spasms: Treats discomfort from kidney stones or UTIs.

    • Gynecological Use: Reduces labor pains (off-label) and dysmenorrhea.

    Side Effects:

    • Common: Dizziness, nausea, mild headache.

    • Rare:

      • Allergic reactions (rash, itching).

      • Low blood pressure (with high doses).

      • Rapid heartbeat (tachycardia).

    Br120.00

    Drotaverine

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  • Darifenacin

    Applications:

    • Overactive Bladder (OAB): Treats frequent urination, urgency, and incontinence.

    • Neurogenic Detrusor Overactivity: Manages bladder control issues in neurological conditions (e.g., MS, spinal cord injury).

    Side Effects:

    • Common: Dry mouth, constipation, blurred vision, dizziness.

    • Serious (Rare):

      • Severe allergic reactions (rash, swelling).

      • Worsening glaucoma (caution in patients with eye conditions).

      • Urinary retention (in men with prostate enlargement).

    Br120.00

    Darifenacin

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  • Atropine Sulphate

    Applications:

    • Pre-Anesthesia: Reduces saliva and respiratory secretions before surgery.

    • Bradycardia: Emergency treatment for abnormally slow heart rate.

    • Poison Antidote: Countacts organophosphate or nerve agent poisoning.

    • Ophthalmic Use: Dilates pupils for eye exams or inflammation treatment.

    • GI Disorders: Relieves spasms in irritable bowel (rarely used today).

    Side Effects:

    • Common: Dry mouth, blurred vision, rapid heartbeat, dizziness.

    • Serious:

      • Hallucinations/confusion (high doses)

      • Urinary retention

      • Glaucoma attacks (with eye drops)

      • Dangerous tachycardia (overdose)

    Note:

    • IV/IM use only in emergencies (hospital/EMS).

    • Reverses life-threatening cholinergic toxicity (e.g., pesticide poisoning).

    Br120.00

    Atropine Sulphate

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  • Nizatidine

    Applications:

    • Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and conditions related to excess stomach acid.
    • Helps reduce acid production in the stomach, promoting healing and alleviating symptoms like heartburn.

    Side Effects:

    • Headache, dizziness, and constipation.
    • In rare cases, can cause liver issues or confusion, especially in older adults.

    Nizatidine is effective in managing acid-related gastrointestinal conditions, but it can cause mild side effects like headache and constipation. Serious side effects are rare but should be monitored, particularly in individuals with liver issues.

    Br120.00

    Nizatidine

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