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Hyoscine/Scopolamine Hydrobromide
Hyoscine/Scopolamine Hydrobromide is an anticholinergic used to prevent motion sickness and treat nausea.
Applications:
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Prevents motion sickness-related nausea and vomiting.
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Used for postoperative nausea and in palliative care to reduce secretions.
Side Effects:
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Common: dry mouth, drowsiness, blurred vision, and dizziness.
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Serious (rare): confusion, hallucinations, and urinary retention.
Br120.00Hyoscine/Scopolamine Hydrobromide
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00Fosaprepitant
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Br120.00
Dexamethasone
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00Aprepitant
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Pantoprazole
Applications:
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Treats GERD & erosive esophagitis
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Manages peptic ulcers (including NSAID-induced)
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Controls Zollinger-Ellison syndrome acid hypersecretion
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Prevents stress ulcers in critical care patients
Side Effects:
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Common: Headache, diarrhea, nausea, abdominal pain
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Serious (rare):
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Kidney inflammation (interstitial nephritis)
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Low magnesium (with prolonged use)
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Vitamin B12 deficiency (long-term therapy)
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Note:
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IV form is preferred for acute bleeding ulcers (80mg bolus, then infusion).
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Requires monitoring: Mg²⁺ levels if used >1 year.
Br120.00Pantoprazole
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Pantoprazole
Applications:
- Used to treat gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers.
- Reduces stomach acid, promoting healing of the esophagus and ulcers.
- Used in treating Zollinger-Ellison syndrome (excessive acid production).
Side Effects:
- Headache, diarrhea, nausea, and abdominal pain.
- In rare cases, can cause low magnesium levels, bone fractures, and kidney issues with long-term use.
Pantoprazole is effective in managing acid-related gastrointestinal conditions but may cause mild side effects like headache and stomach discomfort. Serious side effects are rare but should be monitored, especially with prolonged use or in individuals with kidney concerns.
Br120.00Pantoprazole
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Esomeprazole
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
- Helps reduce stomach acid production, promoting healing and preventing acid-related damage.
Side Effects:
- Headache, nausea, and diarrhea.
- Long-term use may increase the risk of fractures, kidney issues, and vitamin B12 deficiency.
Esomeprazole is effective in reducing acid production, helping treat GERD and ulcers, but prolonged use can lead to some serious side effects, especially with prolonged therapy. It’s important to monitor for any complications, particularly with long-term use.
Br120.00Esomeprazole
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