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Metoclopramide Hydrochloride
Metoclopramide Hydrochloride is a dopamine antagonist used to treat nausea, vomiting, and delayed gastric emptying.
Applications:
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Treats nausea and vomiting from various causes, including chemotherapy and migraines.
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Manages gastroparesis by enhancing stomach motility.
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Used for GERD when other treatments fail.
Side Effects:
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Common: drowsiness, fatigue, restlessness.
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Serious (rare): tardive dyskinesia (involuntary movements), Parkinson-like symptoms, depression.
Br120.00Metoclopramide Hydrochloride
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Meclizine Hydrochloride
Meclizine Hydrochloride is an antihistamine used to treat motion sickness and vertigo.
Applications:
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Prevents and treats nausea, vomiting, and dizziness from motion sickness.
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Manages vertigo from inner ear disorders like Ménière’s disease.
Side Effects:
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Common: drowsiness, dry mouth, and blurred vision.
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Serious (rare): confusion, especially in older adults.
Br120.00Meclizine Hydrochloride
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00Fosaprepitant
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Br120.00
Dexamethasone
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00Aprepitant
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Esomeprazole
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
- Helps reduce stomach acid production, promoting healing and preventing acid-related damage.
Side Effects:
- Headache, nausea, and diarrhea.
- Long-term use may increase the risk of fractures, kidney issues, and vitamin B12 deficiency.
Esomeprazole is effective in reducing acid production, helping treat GERD and ulcers, but prolonged use can lead to some serious side effects, especially with prolonged therapy. It’s important to monitor for any complications, particularly with long-term use.
Br120.00Esomeprazole
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Chlordiazepoxide + Clidinium Bromide.
Chlordiazepoxide + Clidinium Bromide:
Applications:
- Used to treat irritable bowel syndrome (IBS) and other gastrointestinal disorders with spasm or pain.
- Helps manage anxiety and agitation associated with gastrointestinal conditions.
Side Effects:
- Drowsiness, dizziness, and blurred vision.
- Dry mouth, constipation, and urinary retention.
This combination helps reduce symptoms of both gastrointestinal discomfort and anxiety, though it can cause sedation and other common side effects like dry mouth. Be cautious when operating machinery or driving.
Br120.00Chlordiazepoxide + Clidinium Bromide.
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