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Promethazine Hydrochloride
Promethazine Hydrochloride is an antihistamine with antiemetic, sedative, and anticholinergic properties.
Applications:
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Treats nausea, vomiting, and motion sickness.
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Used as a sedative or for allergy symptoms.
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Sometimes used pre/post-surgery for nausea control.
Side Effects:
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Common: drowsiness, dry mouth, dizziness.
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Serious (rare): respiratory depression (especially in children), severe tissue damage if injected improperly.
Br120.00Promethazine Hydrochloride
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00Fosaprepitant
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00Aprepitant
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Propranolol
Applications:
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Heart: Treats high BP, angina, arrhythmias, prevents heart attacks
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Migraines: Reduces frequency
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Anxiety: Controls physical symptoms (shaking, fast heartbeat)
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Hyperthyroidism: Manages symptoms like rapid pulse
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Essential tremor: Decreases shaking
Side Effects:
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Common: Fatigue, dizziness, cold hands/feet, sleep issues
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Serious (rare):
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Slow heart rate, wheezing (caution in asthma patients)
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Worsening heart failure, depression
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Note:
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Avoid sudden stoppage (taper gradually).
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Brands: Inderal®, Hemangeol®, generics.
Monitor heart rate & BP. Not for asthma/COPD patients.
Br120.00Propranolol
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Omeprazole
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and conditions related to excess stomach acid.
- Helps reduce acid production in the stomach, promoting healing and alleviating symptoms like heartburn.
Side Effects:
- Headache, diarrhea, nausea, and abdominal pain.
- In rare cases, it can cause kidney issues, low magnesium levels, or vitamin B12 deficiency with long-term use.
Omeprazole is effective in managing acid-related gastrointestinal conditions but may cause mild side effects like headache and stomach discomfort. Serious side effects are rare but should be monitored, particularly in individuals with kidney problems or those who use it long-term.
Br120.00Omeprazole
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Chlordiazepoxide + Clidinium Bromide.
Chlordiazepoxide + Clidinium Bromide:
Applications:
- Used to treat irritable bowel syndrome (IBS) and other gastrointestinal disorders with spasm or pain.
- Helps manage anxiety and agitation associated with gastrointestinal conditions.
Side Effects:
- Drowsiness, dizziness, and blurred vision.
- Dry mouth, constipation, and urinary retention.
This combination helps reduce symptoms of both gastrointestinal discomfort and anxiety, though it can cause sedation and other common side effects like dry mouth. Be cautious when operating machinery or driving.
Br120.00Chlordiazepoxide + Clidinium Bromide.
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