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Granisetron Hydrochloride
Granisetron Hydrochloride is a 5-HT3 receptor antagonist used to prevent and treat nausea and vomiting.
Applications:
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Prevents nausea and vomiting from chemotherapy and radiation therapy.
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Used postoperatively to manage nausea and vomiting.
Side Effects:
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Common: headache, constipation, dizziness.
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Serious (rare): QT prolongation, allergic reactions.
Br120.00
Granisetron Hydrochloride
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00
Fosaprepitant
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Br120.00
Dexamethasone
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00
Aprepitant
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Omeprazole
Applications:
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Treats severe GERD/ulcers (when oral therapy fails)
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Manages Zollinger-Ellison syndrome (acid hypersecretion)
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Prevents acid aspiration during surgery
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Reduces rebleeding risk after endoscopic treatment
Side Effects:
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Common: Headache, nausea, injection-site pain
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Serious (rare): Kidney injury, low magnesium, bone fractures (long-term use)
Note: Requires kidney/magnesium monitoring with prolonged IV use. Administered once daily (40mg). Brands include Losec® IV and generics.
Br120.00
Omeprazole
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Omeprazole + Sodium Bicarbonate
Omeprazole + Sodium Bicarbonate is a combination used primarily for the treatment of gastroesophageal reflux disease (GERD), acid reflux, and peptic ulcers, similar to sucralfate, but it works differently.
Applications:
- Treats GERD, heartburn, and acid reflux.
- Helps heal and prevent ulcers by reducing stomach acid production.
- Used to manage Zollinger-Ellison syndrome, where excess acid is produced.
Side Effects:
- Common: headache, nausea, diarrhea, and abdominal pain.
- Rare but serious: severe allergic reactions, kidney problems, and bone fractures with long-term use.
- Prolonged use can lead to vitamin B12 deficiency and low magnesium levels.
Unlike sucralfate, which forms a protective layer over ulcers, omeprazole with sodium bicarbonate works by reducing stomach acid to help heal and prevent damage.
Br120.00
Omeprazole + Sodium Bicarbonate
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Ranitidine
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and conditions where the stomach produces too much acid (like Zollinger-Ellison syndrome).
- Reduces stomach acid production, helping to heal ulcers and manage heartburn or acid reflux.
- Can be used for the prevention and treatment of ulcers and conditions like indigestion.
Side Effects:
- Common side effects include headache, dizziness, constipation, or diarrhea.
- Rare but serious side effects may include liver problems, irregular heartbeats, and severe allergic reactions.
- Long-term use can occasionally lead to vitamin B12 deficiency.
Ranitidine is effective in controlling excess stomach acid but was withdrawn from many markets (including the U.S.) in 2020 due to concerns over a potential carcinogenic impurity. For those still using it, monitoring for side effects is important, especially if taken for prolonged periods.
Br120.00
Ranitidine
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Omeprazole
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and conditions related to excess stomach acid.
- Helps reduce acid production in the stomach, promoting healing and alleviating symptoms like heartburn.
Side Effects:
- Headache, diarrhea, nausea, and abdominal pain.
- In rare cases, it can cause kidney issues, low magnesium levels, or vitamin B12 deficiency with long-term use.
Omeprazole is effective in managing acid-related gastrointestinal conditions but may cause mild side effects like headache and stomach discomfort. Serious side effects are rare but should be monitored, particularly in individuals with kidney problems or those who use it long-term.
Br120.00
Omeprazole
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