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Palonosetron Hydrochloride
Palonosetron Hydrochloride is a long-acting 5-HT3 receptor antagonist used to prevent nausea and vomiting.
Applications:
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Prevents acute and delayed nausea/vomiting from moderately to highly emetogenic chemotherapy.
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Also used for postoperative nausea and vomiting.
Side Effects:
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Common: headache, constipation, dizziness.
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Serious (rare): QT prolongation, hypersensitivity reactions.
Br120.00Palonosetron Hydrochloride
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Chlorpromazine Hydrochloride
Applications:
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Psychosis (schizophrenia, mania)
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Severe nausea/vomiting
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Intractable hiccups
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Acute agitation/sedation
Side Effects:
Common: Drowsiness, dry mouth, constipation, low BP
Serious:-
Muscle spasms (EPS), tardive dyskinesia
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Neuroleptic malignant syndrome (NMS)
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QT prolongation → heart rhythm risk
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Seizures, confusion (elderly)
Avoid in: Glaucoma, Parkinson’s, heart rhythm issues.
Br120.00Chlorpromazine Hydrochloride
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Atropine Sulphate
Applications:
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Pre-Anesthesia: Reduces saliva and respiratory secretions before surgery.
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Bradycardia: Emergency treatment for abnormally slow heart rate.
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Poison Antidote: Countacts organophosphate or nerve agent poisoning.
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Ophthalmic Use: Dilates pupils for eye exams or inflammation treatment.
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GI Disorders: Relieves spasms in irritable bowel (rarely used today).
Side Effects:
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Common: Dry mouth, blurred vision, rapid heartbeat, dizziness.
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Serious:
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Hallucinations/confusion (high doses)
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Urinary retention
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Glaucoma attacks (with eye drops)
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Dangerous tachycardia (overdose)
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Note:
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IV/IM use only in emergencies (hospital/EMS).
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Reverses life-threatening cholinergic toxicity (e.g., pesticide poisoning).
Br120.00Atropine Sulphate
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Pantoprazole
Applications:
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Treats GERD & erosive esophagitis
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Manages peptic ulcers (including NSAID-induced)
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Controls Zollinger-Ellison syndrome acid hypersecretion
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Prevents stress ulcers in critical care patients
Side Effects:
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Common: Headache, diarrhea, nausea, abdominal pain
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Serious (rare):
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Kidney inflammation (interstitial nephritis)
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Low magnesium (with prolonged use)
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Vitamin B12 deficiency (long-term therapy)
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Note:
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IV form is preferred for acute bleeding ulcers (80mg bolus, then infusion).
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Requires monitoring: Mg²⁺ levels if used >1 year.
Br120.00Pantoprazole
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Octreotide
Applications:
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Treats acromegaly (reduces growth hormone)
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Manages neuroendocrine tumors (controls carcinoid/VIPoma symptoms)
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Stops severe GI bleeding (esophageal varices, ulcers)
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Closes pancreatic/intestinal fistulas
Side Effects:
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Common: Nausea, diarrhea, gallstones, blood sugar changes
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Serious (rare): Heart rhythm issues, thyroid dysfunction
Note: Requires monitoring for gallbladder and metabolic effects. Available in short-acting (daily) and long-acting (monthly) forms.
Br120.00Octreotide
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Ranitidine
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and conditions where the stomach produces too much acid (like Zollinger-Ellison syndrome).
- Reduces stomach acid production, helping to heal ulcers and manage heartburn or acid reflux.
- Can be used for the prevention and treatment of ulcers and conditions like indigestion.
Side Effects:
- Common side effects include headache, dizziness, constipation, or diarrhea.
- Rare but serious side effects may include liver problems, irregular heartbeats, and severe allergic reactions.
- Long-term use can occasionally lead to vitamin B12 deficiency.
Ranitidine is effective in controlling excess stomach acid but was withdrawn from many markets (including the U.S.) in 2020 due to concerns over a potential carcinogenic impurity. For those still using it, monitoring for side effects is important, especially if taken for prolonged periods.
Br120.00Ranitidine
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Pantoprazole
Applications:
- Used to treat gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers.
- Reduces stomach acid, promoting healing of the esophagus and ulcers.
- Used in treating Zollinger-Ellison syndrome (excessive acid production).
Side Effects:
- Headache, diarrhea, nausea, and abdominal pain.
- In rare cases, can cause low magnesium levels, bone fractures, and kidney issues with long-term use.
Pantoprazole is effective in managing acid-related gastrointestinal conditions but may cause mild side effects like headache and stomach discomfort. Serious side effects are rare but should be monitored, especially with prolonged use or in individuals with kidney concerns.
Br120.00Pantoprazole
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Esomeprazole
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
- Helps reduce stomach acid production, promoting healing and preventing acid-related damage.
Side Effects:
- Headache, nausea, and diarrhea.
- Long-term use may increase the risk of fractures, kidney issues, and vitamin B12 deficiency.
Esomeprazole is effective in reducing acid production, helping treat GERD and ulcers, but prolonged use can lead to some serious side effects, especially with prolonged therapy. It’s important to monitor for any complications, particularly with long-term use.
Br120.00Esomeprazole
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