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Lactulose
Lactulose is an osmotic laxative used to treat constipation and manage hepatic encephalopathy.
Applications:
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Relieves chronic constipation by drawing water into the bowel.
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Reduces blood ammonia levels in patients with liver disease (hepatic encephalopathy).
Side Effects:
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Common: bloating, gas, abdominal cramps, diarrhea.
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Serious (rare): electrolyte imbalance with prolonged use or high doses.
Br120.00
Lactulose
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Hyoscine/Scopolamine Hydrobromide
Hyoscine/Scopolamine Hydrobromide is an anticholinergic used to prevent motion sickness and treat nausea.
Applications:
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Prevents motion sickness-related nausea and vomiting.
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Used for postoperative nausea and in palliative care to reduce secretions.
Side Effects:
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Common: dry mouth, drowsiness, blurred vision, and dizziness.
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Serious (rare): confusion, hallucinations, and urinary retention.
Br120.00
Hyoscine/Scopolamine Hydrobromide
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00
Fosaprepitant
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00
Aprepitant
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Oxybutynin
Applications:
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Overactive Bladder (OAB): Reduces urgency, frequency, and incontinence.
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Neurogenic Bladder: Manages urinary leakage in spinal cord injury/MS.
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Pediatric Enuresis: Treats bedwetting (off-label in children ≥5 yrs).
Side Effects:
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Common: Dry mouth (70% of users), constipation, blurred vision, drowsiness.
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Serious (Rare):
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Urinary retention (risk in prostate enlargement).
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Heatstroke (reduced sweating in high temperatures).
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CNS effects (confusion in elderly).
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Br120.00
Oxybutynin
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Mebeverine
Applications:
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Irritable Bowel Syndrome (IBS): Relieves abdominal pain, bloating, and cramps.
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Functional GI Disorders: Manages spasms in conditions like diverticulitis.
Side Effects:
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Common: Mild dizziness, headache, nausea.
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Rare:
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Allergic reactions (rash, itching).
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Constipation or diarrhea.
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Br120.00
Mebeverine
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Drotaverine
Applications:
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Abdominal Pain: Relieves cramps in IBS, gastritis, or menstrual discomfort.
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Biliary Colic: Eases spasms in gallbladder/bile duct disorders.
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Urinary Tract Spasms: Treats discomfort from kidney stones or UTIs.
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Gynecological Use: Reduces labor pains (off-label) and dysmenorrhea.
Side Effects:
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Common: Dizziness, nausea, mild headache.
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Rare:
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Allergic reactions (rash, itching).
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Low blood pressure (with high doses).
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Rapid heartbeat (tachycardia).
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Br120.00
Drotaverine
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Nizatidine
Applications:
- Used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and conditions related to excess stomach acid.
- Helps reduce acid production in the stomach, promoting healing and alleviating symptoms like heartburn.
Side Effects:
- Headache, dizziness, and constipation.
- In rare cases, can cause liver issues or confusion, especially in older adults.
Nizatidine is effective in managing acid-related gastrointestinal conditions, but it can cause mild side effects like headache and constipation. Serious side effects are rare but should be monitored, particularly in individuals with liver issues.
Br120.00
Nizatidine
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