Palonosetron Hydrochloride is a long-acting 5-HT3 receptor antagonist used to prevent nausea and vomiting.

Applications:

• Prevents acute and delayed nausea/vomiting from moderately to highly emetogenic chemotherapy.

• Also used for postoperative nausea and vomiting.

Side Effects:

• Common: headache, constipation, dizziness.

• Serious (rare): QT prolongation, hypersensitivity reactions.

Hyoscine/Scopolamine Hydrobromide is an anticholinergic used to prevent motion sickness and treat nausea.

Applications:

• Prevents motion sickness-related nausea and vomiting.

• Used for postoperative nausea and in palliative care to reduce secretions.

Side Effects:

• Common: dry mouth, drowsiness, blurred vision, and dizziness.

• Serious (rare): confusion, hallucinations, and urinary retention.

Dimenhydrinate is an antihistamine primarily used to prevent and treat motion sickness and nausea.

Applications:

• Prevents and relieves nausea, vomiting, and dizziness from motion sickness.

• Used for vertigo and inner ear disturbances like Ménière’s disease.

Side Effects:

• Common: drowsiness, dry mouth, dizziness, and blurred vision.

• Serious (rare): confusion (especially in elderly), fast heartbeat, and urinary retention.