Applications:

• Bloating & Gas Relief:

  • Simethicone: Breaks down gas bubbles in the gut (anti-foaming agent).

  • Alverine Citrate: Relieves intestinal spasms (smooth muscle relaxant).

• Irritable Bowel Syndrome (IBS): Reduces cramping, distension, and discomfort.

• Functional GI Disorders: Eases symptoms of dyspepsia or diverticular disease.

Side Effects:

• Simethicone: Generally side-effect-free (not absorbed systemically).

• Alverine Citrate:

  • Mild: Dizziness, nausea, headache.

  • Rare: Allergic reactions (rash, itching).

Applications:

• Overactive Bladder (OAB): Reduces urgency, frequency, and incontinence.

• Neurogenic Bladder: Manages urinary leakage in spinal cord injury/MS.

• Pediatric Enuresis: Treats bedwetting (off-label in children ≥5 yrs).

Side Effects:

• Common: Dry mouth (70% of users), constipation, blurred vision, drowsiness.

• Serious (Rare):

  • Urinary retention (risk in prostate enlargement).

  • Heatstroke (reduced sweating in high temperatures).

  • CNS effects (confusion in elderly).

Applications:

• Irritable Bowel Syndrome (IBS): Relieves abdominal pain, bloating, and cramps.

• Functional GI Disorders: Manages spasms in conditions like diverticulitis.

Side Effects:

• Common: Mild dizziness, headache, nausea.

• Rare:

  • Allergic reactions (rash, itching).

  • Constipation or diarrhea.

Applications:

• GI Spasms: Treats irritable bowel syndrome (IBS), diverticulitis, and abdominal cramps.

• Biliary/Urinary Colic: Relieves pain from gallstones or kidney stones.

• Endoscopic Procedures: Reduces intestinal motility during colonoscopy.

• Menstrual Cramps: Eases dysmenorrhea (off-label use).

Side Effects:

• Common: Dry mouth, dizziness, blurred vision (mild anticholinergic effects).

• Serious (Rare):

  • Tachycardia (fast heart rate).

  • Urinary retention (especially in elderly men with prostate issues).

  • Allergic reactions (rash, anaphylaxis).