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Cascara sagrada
Cascara Sagrada is a natural stimulant laxative derived from the bark of the Rhamnus purshiana tree.
Applications:
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Used to relieve occasional constipation.
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Sometimes included in herbal detox or colon cleanse products.
Side Effects:
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Common: abdominal cramps, diarrhea.
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Serious (with long-term use): electrolyte imbalance, dependency, liver damage (rare).
Br120.00Cascara sagrada
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Ondansetron
Ondansetron is a 5-HT3 receptor antagonist used to prevent and treat nausea and vomiting.
Applications:
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Prevents nausea and vomiting from chemotherapy, radiation, and surgery.
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Sometimes used for severe morning sickness in pregnancy.
Side Effects:
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Common: headache, constipation, dizziness.
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Serious (rare): QT prolongation, allergic reactions, serotonin syndrome (when combined with other serotonergic drugs).
Br120.00Ondansetron
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00Fosaprepitant
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Doxylamine succinate + Pyridoxine Hydrochloride
Doxylamine Succinate + Pyridoxine Hydrochloride is a combination used to treat nausea and vomiting during pregnancy (morning sickness).
Applications:
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First-line treatment for morning sickness in pregnant women.
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Helps reduce nausea and vomiting without harming the fetus.
Side Effects:
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Common: drowsiness, dry mouth, dizziness, and headache.
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Serious (rare): allergic reactions, confusion, and difficulty urinating.
Br120.00Doxylamine succinate + Pyridoxine Hydrochloride
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00Aprepitant
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Rabeprazole sodium
Applications:
- Used to treat gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers.
- Reduces stomach acid, promoting healing of the esophagus and ulcers.
- Effective in treating Zollinger-Ellison syndrome (excessive acid production).
Side Effects:
- Common side effects include headache, diarrhea, nausea, and abdominal pain.
- Rare side effects include low magnesium levels, bone fractures, and kidney issues, especially with prolonged use.
Rabeprazole sodium is a helpful treatment for acid-related gastrointestinal issues but, like other proton pump inhibitors, may lead to mild side effects such as headaches or stomach discomfort. Serious side effects are uncommon but should be monitored, especially during long-term use or in individuals with kidney concerns.