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Hyoscine/Scopolamine Hydrobromide
Hyoscine/Scopolamine Hydrobromide is an anticholinergic used to prevent motion sickness and treat nausea.
Applications:
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Prevents motion sickness-related nausea and vomiting.
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Used for postoperative nausea and in palliative care to reduce secretions.
Side Effects:
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Common: dry mouth, drowsiness, blurred vision, and dizziness.
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Serious (rare): confusion, hallucinations, and urinary retention.
Br120.00Hyoscine/Scopolamine Hydrobromide
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00Fosaprepitant
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00Aprepitant
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Tolterodine
Applications:
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Overactive Bladder (OAB): Treats urinary frequency, urgency, and incontinence.
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Neurogenic Detrusor Overactivity: Manages bladder spasms in neurological conditions (e.g., MS, spinal injury).
Side Effects:
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Common: Dry mouth (35% of users), constipation, blurred vision, headache.
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Serious (Rare):
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QT prolongation (caution in heart disease).
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Angioedema (swelling of face/throat).
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Urinary retention (risk in prostate enlargement).
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Br120.00Tolterodine
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Drotaverine
Applications:
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Abdominal Pain: Relieves cramps in IBS, gastritis, or menstrual discomfort.
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Biliary Colic: Eases spasms in gallbladder/bile duct disorders.
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Urinary Tract Spasms: Treats discomfort from kidney stones or UTIs.
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Gynecological Use: Reduces labor pains (off-label) and dysmenorrhea.
Side Effects:
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Common: Dizziness, nausea, mild headache.
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Rare:
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Allergic reactions (rash, itching).
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Low blood pressure (with high doses).
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Rapid heartbeat (tachycardia).
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Br120.00Drotaverine
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Darifenacin
Applications:
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Overactive Bladder (OAB): Treats frequent urination, urgency, and incontinence.
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Neurogenic Detrusor Overactivity: Manages bladder control issues in neurological conditions (e.g., MS, spinal cord injury).
Side Effects:
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Common: Dry mouth, constipation, blurred vision, dizziness.
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Serious (Rare):
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Severe allergic reactions (rash, swelling).
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Worsening glaucoma (caution in patients with eye conditions).
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Urinary retention (in men with prostate enlargement).
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Br120.00Darifenacin
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Rabeprazole sodium
Applications:
- Used to treat gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers.
- Reduces stomach acid, promoting healing of the esophagus and ulcers.
- Effective in treating Zollinger-Ellison syndrome (excessive acid production).
Side Effects:
- Common side effects include headache, diarrhea, nausea, and abdominal pain.
- Rare side effects include low magnesium levels, bone fractures, and kidney issues, especially with prolonged use.
Rabeprazole sodium is a helpful treatment for acid-related gastrointestinal issues but, like other proton pump inhibitors, may lead to mild side effects such as headaches or stomach discomfort. Serious side effects are uncommon but should be monitored, especially during long-term use or in individuals with kidney concerns.