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Propantheline Bromide
Applications:
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Peptic Ulcers: Reduces gastric acid secretion (adjunct therapy).
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Hyperhidrosis: Controls excessive sweating (off-label).
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GI Spasms: Manages irritable bowel syndrome (IBS) and diverticulitis.
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Urinary Incontinence: Treats overactive bladder (less common now).
Side Effects:
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Common: Dry mouth, blurred vision, constipation, drowsiness.
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Serious (Rare):
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Urinary retention (risk in prostate enlargement).
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Tachycardia (fast heart rate).
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Glaucoma exacerbation (avoid in narrow-angle glaucoma).
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Br120.00Propantheline Bromide
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Simethicone + Algerines citrate
Applications:
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Bloating & Gas Relief:
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Simethicone: Breaks down gas bubbles in the gut (anti-foaming agent).
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Alverine Citrate: Relieves intestinal spasms (smooth muscle relaxant).
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Irritable Bowel Syndrome (IBS): Reduces cramping, distension, and discomfort.
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Functional GI Disorders: Eases symptoms of dyspepsia or diverticular disease.
Side Effects:
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Simethicone: Generally side-effect-free (not absorbed systemically).
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Alverine Citrate:
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Mild: Dizziness, nausea, headache.
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Rare: Allergic reactions (rash, itching).
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Br120.00Simethicone + Algerines citrate
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Tolterodine
Applications:
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Overactive Bladder (OAB): Treats urinary frequency, urgency, and incontinence.
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Neurogenic Detrusor Overactivity: Manages bladder spasms in neurological conditions (e.g., MS, spinal injury).
Side Effects:
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Common: Dry mouth (35% of users), constipation, blurred vision, headache.
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Serious (Rare):
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QT prolongation (caution in heart disease).
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Angioedema (swelling of face/throat).
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Urinary retention (risk in prostate enlargement).
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Br120.00Tolterodine
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Aprepitant
Applications:
Chemotherapy-Induced Nausea/Vomiting (CINV): Prevents acute/delayed nausea from highly emetogenic chemo (e.g., cisplatin).
Moderately Emetogenic Chemo: Used with dexamethasone + 5-HT3 blockers (e.g., ondansetron).
Postoperative Nausea/Vomiting (PONV): Alternative for high-risk surgeries (less common).Side Effects:
Common: Fatigue, hiccups, constipation, headache, loss of appetite.
Serious (Rare):-
Liver toxicity (elevated LFTs).
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Hypersensitivity (rash, anaphylaxis).
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Drug interactions (CYP3A4 inhibitor—affects warfarin, birth control, some chemo drugs).
Note: Avoid with pimozide (QT prolongation risk). IV form (fosaprepitant) available.
Br120.00Aprepitant
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Chlorpromazine Hydrochloride
Applications:
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Psychosis (schizophrenia, mania)
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Severe nausea/vomiting
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Intractable hiccups
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Acute agitation/sedation
Side Effects:
Common: Drowsiness, dry mouth, constipation, low BP
Serious:-
Muscle spasms (EPS), tardive dyskinesia
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Neuroleptic malignant syndrome (NMS)
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QT prolongation → heart rhythm risk
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Seizures, confusion (elderly)
Avoid in: Glaucoma, Parkinson’s, heart rhythm issues.
Br120.00Chlorpromazine Hydrochloride
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Br120.00
Dexamethasone
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Dimenhydrinate
Dimenhydrinate is an antihistamine primarily used to prevent and treat motion sickness and nausea.
Applications:
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Prevents and relieves nausea, vomiting, and dizziness from motion sickness.
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Used for vertigo and inner ear disturbances like Ménière’s disease.
Side Effects:
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Common: drowsiness, dry mouth, dizziness, and blurred vision.
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Serious (rare): confusion (especially in elderly), fast heartbeat, and urinary retention.
Br120.00Dimenhydrinate
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Doxylamine succinate + Pyridoxine Hydrochloride
Doxylamine Succinate + Pyridoxine Hydrochloride is a combination used to treat nausea and vomiting during pregnancy (morning sickness).
Applications:
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First-line treatment for morning sickness in pregnant women.
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Helps reduce nausea and vomiting without harming the fetus.
Side Effects:
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Common: drowsiness, dry mouth, dizziness, and headache.
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Serious (rare): allergic reactions, confusion, and difficulty urinating.
Br120.00Doxylamine succinate + Pyridoxine Hydrochloride
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Domperidone
Domperidone is a dopamine antagonist used to treat nausea, vomiting, and gastrointestinal motility disorders.
Applications:
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Relieves nausea and vomiting.
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Treats gastroparesis by enhancing stomach emptying.
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Sometimes used to increase breast milk production (off-label).
Side Effects:
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Common: dry mouth, abdominal cramps, and headache.
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Serious (rare): heart rhythm disorders, especially in elderly or high doses.
Br120.00Domperidone
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Fosaprepitant
Fosaprepitant is an antiemetic used to prevent nausea and vomiting caused by chemotherapy.
Applications:
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Prevents acute and delayed nausea/vomiting from highly emetogenic chemotherapy.
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Often used in combination with other antiemetics (like dexamethasone and a 5-HT3 antagonist).
Side Effects:
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Common: fatigue, headache, hiccups, and constipation.
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Serious (rare): infusion site reactions, allergic reactions, liver enzyme elevation.
Brands: Emend (IV).
Br120.00Fosaprepitant
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Granisetron Hydrochloride
Granisetron Hydrochloride is a 5-HT3 receptor antagonist used to prevent and treat nausea and vomiting.
Applications:
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Prevents nausea and vomiting from chemotherapy and radiation therapy.
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Used postoperatively to manage nausea and vomiting.
Side Effects:
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Common: headache, constipation, dizziness.
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Serious (rare): QT prolongation, allergic reactions.
Br120.00Granisetron Hydrochloride
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Hyoscine/Scopolamine Hydrobromide
Hyoscine/Scopolamine Hydrobromide is an anticholinergic used to prevent motion sickness and treat nausea.
Applications:
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Prevents motion sickness-related nausea and vomiting.
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Used for postoperative nausea and in palliative care to reduce secretions.
Side Effects:
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Common: dry mouth, drowsiness, blurred vision, and dizziness.
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Serious (rare): confusion, hallucinations, and urinary retention.
Br120.00Hyoscine/Scopolamine Hydrobromide
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Meclizine Hydrochloride
Meclizine Hydrochloride is an antihistamine used to treat motion sickness and vertigo.
Applications:
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Prevents and treats nausea, vomiting, and dizziness from motion sickness.
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Manages vertigo from inner ear disorders like Ménière’s disease.
Side Effects:
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Common: drowsiness, dry mouth, and blurred vision.
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Serious (rare): confusion, especially in older adults.
Br120.00Meclizine Hydrochloride
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Meclizine Hydrochloride+ Pyridoxine hydrochloride
Meclizine Hydrochloride + Pyridoxine Hydrochloride is a combination used to manage nausea, vomiting, and vertigo.
Applications:
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Treats nausea and vomiting, especially in pregnancy and motion sickness.
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Helps manage vertigo and dizziness related to inner ear issues.
Side Effects:
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Common: drowsiness, dry mouth, and dizziness.
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Serious (rare): confusion, allergic reactions.
Br120.00Meclizine Hydrochloride+ Pyridoxine hydrochloride
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Metoclopramide Hydrochloride
Metoclopramide Hydrochloride is a dopamine antagonist used to treat nausea, vomiting, and delayed gastric emptying.
Applications:
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Treats nausea and vomiting from various causes, including chemotherapy and migraines.
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Manages gastroparesis by enhancing stomach motility.
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Used for GERD when other treatments fail.
Side Effects:
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Common: drowsiness, fatigue, restlessness.
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Serious (rare): tardive dyskinesia (involuntary movements), Parkinson-like symptoms, depression.
Br120.00Metoclopramide Hydrochloride
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Ondansetron
Ondansetron is a 5-HT3 receptor antagonist used to prevent and treat nausea and vomiting.
Applications:
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Prevents nausea and vomiting from chemotherapy, radiation, and surgery.
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Sometimes used for severe morning sickness in pregnancy.
Side Effects:
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Common: headache, constipation, dizziness.
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Serious (rare): QT prolongation, allergic reactions, serotonin syndrome (when combined with other serotonergic drugs).
Br120.00Ondansetron
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Palonosetron Hydrochloride
Palonosetron Hydrochloride is a long-acting 5-HT3 receptor antagonist used to prevent nausea and vomiting.
Applications:
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Prevents acute and delayed nausea/vomiting from moderately to highly emetogenic chemotherapy.
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Also used for postoperative nausea and vomiting.
Side Effects:
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Common: headache, constipation, dizziness.
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Serious (rare): QT prolongation, hypersensitivity reactions.
Br120.00Palonosetron Hydrochloride
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Promethazine Hydrochloride
Promethazine Hydrochloride is an antihistamine with antiemetic, sedative, and anticholinergic properties.
Applications:
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Treats nausea, vomiting, and motion sickness.
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Used as a sedative or for allergy symptoms.
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Sometimes used pre/post-surgery for nausea control.
Side Effects:
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Common: drowsiness, dry mouth, dizziness.
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Serious (rare): respiratory depression (especially in children), severe tissue damage if injected improperly.
Br120.00Promethazine Hydrochloride
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