Palonosetron Hydrochloride is a long-acting 5-HT3 receptor antagonist used to prevent nausea and vomiting.

Applications:

• Prevents acute and delayed nausea/vomiting from moderately to highly emetogenic chemotherapy.

• Also used for postoperative nausea and vomiting.

Side Effects:

• Common: headache, constipation, dizziness.

• Serious (rare): QT prolongation, hypersensitivity reactions.